The Alzheimer’s Disease Genetics Consortium (ADGC) is a collaborative effort that brings together researchers from multiple institutions to study the genetics of Alzheimer’s disease. The primary goal of ADGC is to identify and understand genetic factors that contribute to the risk of developing Alzheimer’s disease and related dementias. By analyzing large-scale genomic data, ADGC aims to uncover genetic variants and mutations associated with the disease, which can lead to a better understanding of the underlying biological mechanisms and potential targets for therapeutic interventions.
The ADGC will provide the most recent and most comprehensive data available. The data sets available are listed on the ADGC Web site (link). These data are QC’ed by members of the ADGC-AC using a uniform process. As noted in the list of cohorts posted on the ADGC web site, some datasets require permission of the PI who contributed the dataset, and it is the responsibility of the SAG PI to seek permission from those PIs to use their data. If requested, imputed data will be provided using the most recent and largest imputation panel (e.g. TOPMed). A minimum phenotype dataset will be provided. If additional phenotypes are needed, the ADGC will work with the investigator to identify and acquire the needed data.
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