The Translational Neuropathology Research Laboratory seeks to understand the molecular causes of age-related neurodegenerative diseases, in particular frontotemporal degeneration (FTD), amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD) and Trauma-Related Neurodegeneration (TReND). They use an interdisciplinary approach to address the mechanisms of neurodegeneration, including molecular, biochemical, histologic, physiologic and behavioral methods. They are also interested in using and developing cutting-edge techniques including multi-spectral confocal imaging, single cell RNA sequencing, spatial transcriptomics, CRISPR editing, and cryo-electron microscopy.
View Resource
